Generation of bone marrow chimeras using X-ray irradiation: comparison to cesium irradiation and use in immunotherapy.

Bone marrow chimeras represent a key tool employed to understand biological contributions stemming from the hematopoietic versus the stromal compartment. In most institutions, cesium irradiators are used to lethally irradiate recipient animals prior to the injection of donor bone marrow. Cesium irradiators, however, have significant liabilities-including concerns around domestic security. Recently, X-ray irradiators have been implemented as a potential alternative to cesium sources.

Only a small number of publications in the literature have attempted to compare these two modalities and, in most cases, the emphasis was on irradiation of human blood productions. We were able to find only a single study that directly compared X-ray and cesium technologies in the generation of murine bone marrow chimeras, a standard laboratory practice. This study focused on chimerism in the blood of recipient animals.

KT 5720

B9002-.1 100 µg
EUR 232.00

KT 5720

B9002-.25 250 µg
EUR 483.00

KT 5720

B9002-.5 500 µg
EUR 818.00

KT 5823

20-abx076629
  • EUR 356.00
  • EUR 829.00
  • 100 ug
  • 500 ug
  • Shipped within 5-12 working days.

KT 5823

B6673-.05 50 µg
EUR 123.00

KT 5823

B6673-.1 100 µg
EUR 190.00

KT 5823

B6673-.25 250 µg
EUR 361.00

PST- KT

PVT11358 2 ug
EUR 370.00

iFluor™ 680 hydrazide

1086 1 mg
EUR 219.00
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12171501

Mouse Olfactory receptor 1086, Olfr1086 ELISA KIT

ELI-46106m 96 Tests
EUR 865.00

Plasminogen Receptor (KT) (PLGRKT) Antibody

20-abx318476
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

KT 5823 (PKG kinase inhibitor)

SIH-458-100UG 100 µg
EUR 205.00
  • KT5823 is a potent, selective, and reversible inhibitor of Protein Kinase G (PKG). It is a derivative of K-252a. KT5823 has been shown to inhibit SNP-stimulated PKG activity in dispersed smooth muscle cells. It has also been observed to dose-dependen
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Description: The substance KT 5823 is a pkg kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is white solid which is soluble in DMSO (20 mg/ml), dimethyl formamide (20 mg/ml) and ethyl acetate (5 mg/ml).

KT 5823 (PKG kinase inhibitor)

SIH-458-500UG 500 µg
EUR 569.00
  • KT5823 is a potent, selective, and reversible inhibitor of Protein Kinase G (PKG). It is a derivative of K-252a. KT5823 has been shown to inhibit SNP-stimulated PKG activity in dispersed smooth muscle cells. It has also been observed to dose-dependen
  • Show more
Description: The substance KT 5823 is a pkg kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is white solid which is soluble in DMSO (20 mg/ml), dimethyl formamide (20 mg/ml) and ethyl acetate (5 mg/ml).

Rat Chondroitin Sulfate Epitope 3B3(CS3B3 ELISA Kt

GA-E0451RT-48T 48T
EUR 317.00

Rat Chondroitin Sulfate Epitope 3B3(CS3B3 ELISA Kt

GA-E0451RT-96T 96T
EUR 496.00

Rat Chondroitin Sulfate Epitope 3B3(CS3B3 ELISA Kt

QY-E11201 96T
EUR 361.00

Mouse Chondroitin Sulfate Epitope 3B3(CS3B3 ELISA Kt

QY-E20317 96T
EUR 361.00

Cyclophilin B antibody

10R-1086 100 ul
EUR 316.00
Description: Mouse monoclonal Cyclophilin B antibody

Caspase-6, human recombinant

1086-100
EUR 452.00

Caspase-6, human recombinant

1086-25
EUR 283.00

Goat anti Rat IgG (H + L)

41R-1086 2 mg
EUR 137.00
Description: Goat anti Rat IgG (H + L) secondary antibody

Rabbit anti Goat IgG Fc (biotin)

43R-1086 1 mg
EUR 322.00
Description: Rabbit anti Goat IgG Fc fragment secondary antibody (biotin)

17b Testosterone-HRP

80-1086 500 ul
EUR 248.00
Description: 17b-Testosterone 7 Conjugate for use in immunoassays

UBE2L6 protein (His tag)

80R-1086 100 ug
EUR 397.00
Description: Purified recombinant Human UBE2L6 protein

ZNF12 Blocking Peptide

33R-1086 100 ug
EUR 180.00
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of TAF13 antibody, catalog no. 70R-8716

Human IgG2

31R-1086 1 mg
EUR 276.00
Description: Purified native Human IgG2 protein

Complement C3 protein

30-1086 100 ug
EUR 201.00
Description: Purified native Human Complement C3 protein

MLLT4 antibody

20R-1086 100 ug
EUR 377.00
Description: Rabbit polyclonal MLLT4 antibody

Zika virus NS1 antibody

70-1086 500ug
EUR 305.00
Description: Purified Goat polyclonal Zika virus NS1 antibody

LOC339879 antibody

70R-1086 100 ug
EUR 377.00
Description: Rabbit polyclonal LOC339879 antibody raised against the C terminal of LOC339879

HA antibody (HRP)

60R-1086 1 ml
EUR 508.00
Description: Affinity purified Chicken polyclonal HA antibody (HRP)

CD45R antibody (FITC)

61R-1086 100 ug
EUR 165.00
Description: Rat monoclonal CD45R antibody (FITC)

Factor XI Antibody Pair

55R-FAC11-KT 5 plates
EUR 745.00
Description: Factor XI antigen Matched Pair antibody Set for ELISA

Factor IX Antibody Pair

55R-FAC9-KT 5 plates
EUR 760.00
Description: Factor IX antigen Matched Pair antibody Set for ELISA

Fibrinogen Matched Pair antibody Set

55R-FIBRINO-KT set
EUR 833.00
Description: Fibrinogen Matched Pair antibody Set for detection of Human Fibrinogen in the research laboratory

Mouse RANKL ELISA Kit

55R-MRANKL-KT 1 kit
EUR 658.00
Description: ELISA kit for detection of Mouse RANKL in the research laboratory

VWF Antibody Pair

55R-VWF-KT 5 plates
EUR 775.00
Description: VWF antigen Matched Pair antibody Set for ELISA

Human Glomerular tissue extract-advanced glycosylation end products,GTE-AGE ELISA Kit

201-12-1086 96 tests
EUR 440.00
  • This Glomerular tissue extract-advanced glycosylation end products ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Anti-EPCAM (Tucotuzumab)-MC-Vc-PAB-SN38 ADC

ADC-W-1086 1mg Ask for price
Description: This ADC product is comprised of an anti-EPCAM monoclonal antibody conjugated via a MC-Vc-PAB linker to SN38