Gut-derived acetate promotes B10 cells with anti-inflammatory effects

Gut-derived acetate promotes B10 cells with anti-inflammatory effects

Autoimmune ailments are characterised by a breakdown of immune tolerance partly on account of environmental components. The short-chain fatty acid acetate, derived largely from intestine microbial fermentation of dietary fiber, promotes anti-inflammatory regulatory T cells and protects mice from kind 1 diabetes, colitis and allergic reactions. Here, we present that the effects of acetate prolong to a …

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