Immunologic Characteristics of Nonmelanoma Skin Cancers: Implications for Immunotherapy.

In this review, we summarize the immunology of nonmelanoma skin cancers (NMSCs) and the clinical data with immunotherapy in this heterogeneous group of cancers that include basal cell carcinoma (BCC), cutaneous squamous cell carcinoma (CSCC), and Merkel cell carcinoma (MCC). NMSCs are exceedingly common, and their treatment consumes substantial health care resources. Annual global mortality from NMSCs is comparable to that from malignant melanoma.

Although the majority of NMSCs are localized at diagnosis and are treated effectively with surgery, metastases (nodal and distant) can sometimes arise and require systemic therapy. Given the success of immunotherapy in treating cutaneous melanoma, there has been an increasing interest in studying the immunology of NMSCs. 

KT 5823

B6673-.1 100 µg
EUR 190

KT 5823

B6673-.25 250 µg
EUR 361

KT 5720

B9002-.05 50 µg
EUR 145

KT 5720

B9002-.1 100 µg
EUR 232

KT 5720

B9002-.25 250 µg
EUR 483

KT 5720

B9002-.5 500 µg
EUR 818

PST- KT

PVT11358 2 ug
EUR 370

iFluor™ 750 amine

1079 1 mg
EUR 219
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12171501

Plasminogen Receptor (KT) (PLGRKT) Antibody

20-abx318476
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

KT 5823 (PKG kinase inhibitor)

SIH-458-100UG 100 µg
EUR 205
  • KT5823 is a potent, selective, and reversible inhibitor of Protein Kinase G (PKG). It is a derivative of K-252a. KT5823 has been shown to inhibit SNP-stimulated PKG activity in dispersed smooth muscle cells. It has also been observed to dose-dependen
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Description: The substance KT 5823 is a pkg kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is white solid which is soluble in DMSO (20 mg/ml), dimethyl formamide (20 mg/ml) and ethyl acetate (5 mg/ml).

KT 5823 (PKG kinase inhibitor)

SIH-458-500UG 500 µg
EUR 569
  • KT5823 is a potent, selective, and reversible inhibitor of Protein Kinase G (PKG). It is a derivative of K-252a. KT5823 has been shown to inhibit SNP-stimulated PKG activity in dispersed smooth muscle cells. It has also been observed to dose-dependen
  • Show more
Description: The substance KT 5823 is a pkg kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is white solid which is soluble in DMSO (20 mg/ml), dimethyl formamide (20 mg/ml) and ethyl acetate (5 mg/ml).

Rat Chondroitin Sulfate Epitope 3B3(CS3B3 ELISA Kt

GA-E0451RT-48T 48T
EUR 317

Rat Chondroitin Sulfate Epitope 3B3(CS3B3 ELISA Kt

GA-E0451RT-96T 96T
EUR 496

Rat Chondroitin Sulfate Epitope 3B3(CS3B3 ELISA Kt

QY-E11201 96T
EUR 361

Mouse Chondroitin Sulfate Epitope 3B3(CS3B3 ELISA Kt

QY-E20317 96T
EUR 361

BIGH3 protein

30R-1079 100 ug
EUR 305
Description: Purified recombinant Human BIGH3 protein

SP140 antibody

20R-1079 100 ug
EUR 377
Description: Rabbit polyclonal SP140 antibody

FKBP6 antibody

70R-1079 100 ug
EUR 377
Description: Rabbit polyclonal FKBP6 antibody raised against the middle region of FKBP6

PORCN Blocking Peptide

33R-1079 100 ug
EUR 180
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of WDR49 antibody, catalog no. 70R-3399

Rat IgG Fab

31R-1079 1 mg
EUR 457
Description: Purified native IgG Fab protein (Rat)

Caspase-12 Inhibitor Z-ATAD-FMK

1079-100
EUR 218

Caspase-12 Inhibitor Z-ATAD-FMK

1079-20C
EUR 218

PDCD4 antibody

10R-1079 100 ul
EUR 316
Description: Mouse monoclonal PDCD4 antibody

Amikacin antibody

20-1079 100 ul
EUR 879
Description: Sheep polyclonal Amikacin antibody

PAI1 antibody (HRP)

60R-1079 200 ug
EUR 436
Description: Sheep polyclonal PAI1 antibody (HRP) conjugated

CD41 antibody (FITC)

61R-1079 100 ug
EUR 284
Description: Rat monoclonal CD41 antibody (FITC)

Goat anti Rabbit IgG

41R-1079 2 mg
EUR 149
Description: Goat anti Rabbit IgG secondary antibody

Malate dehydrogenase

44R-1079 100 KU
EUR 133
Description: Malate dehydrogenase enzyme

17a Testosterone-HRP

80-1079 500 ul
EUR 417
Description: 17a-Testosterone 3 Conjugate for use in immunoassays

AK2 protein (His tag)

80R-1079 100 ug
EUR 305
Description: Purified recombinant Human AK2 protein

Factor XI Antibody Pair

55R-FAC11-KT 5 plates
EUR 745
Description: Factor XI antigen Matched Pair antibody Set for ELISA

Factor IX Antibody Pair

55R-FAC9-KT 5 plates
EUR 760
Description: Factor IX antigen Matched Pair antibody Set for ELISA

Fibrinogen Matched Pair antibody Set

55R-FIBRINO-KT set
EUR 833
Description: Fibrinogen Matched Pair antibody Set for detection of Human Fibrinogen in the research laboratory

Mouse RANKL ELISA Kit

55R-MRANKL-KT 1 kit
EUR 658
Description: ELISA kit for detection of Mouse RANKL in the research laboratory

VWF Antibody Pair

55R-VWF-KT 5 plates
EUR 775
Description: VWF antigen Matched Pair antibody Set for ELISA

Human Surfactant Protein A,SP-A ELISA Kit

201-12-1079 96 tests
EUR 440
  • This Surfactant Protein A ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Carboxyl Fluorescent Particles

CFP01-1079-3 3 mL
EUR 253
Description: Gentaur distributes carboxyl, functionalized surface groups used for covalent coupling.If you need more technical information please contact our dedicated team via live chat, phone or email.

Anti-EPCAM (Citatuzumab bogatox)-MC-Vc-PAB-MMAE ADC

ADC-W-1079 1mg Ask for price
Description: This ADC product is comprised of an anti-EPCAM monoclonal antibody conjugated via a MC-Vc linker to MMAE